Evolution of Treatment Products—the much anticipated second module in the Treatment Products eLearning program—has launched! This module explains the evolution of products for the treatment of bleeding disorders, from products derived from blood to artificially produced clotting factor concentrates, including those designed to have an extended half-life. An introductory section describes how each type of product provided a breakthrough in care along with the accompanying advances in safety each product delivered. More detailed presentations of each product type explore how they work, how they are produced, whether they can be used to treat hemophilia A and/or B, and their specific advantages and disadvantages. This module also goes over pharmacological alternatives to factor replacement therapy that can reduce the need for blood transfusion and factor concentrates, and touches upon the products used to treat von Willebrand disease (VWD).